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Antibody Glycosylation Analysis
Antibodies, or immunoglobulins, are glycoproteins that play a crucial role in the immune system by recognizing and binding to specific antigens, thereby facilitating their removal from the body. The addition of sugar molecules, or glycans, to antibodies can have a significant impact on their structure, stability, and function. Antibody glycosylation analysis can provide valuable insights into the quality, safety, and efficacy of antibody-based therapeutics. It can help to identify changes in glycosylation patterns that may impact the stability, immunogenicity, or pharmacokinetics of the antibody, and can inform the development and optimization of antibody-based drugs. Yurogen offers antibody glycosylation analysis service with different technology platforms, including; mass spectrometry, high-performance liquid chromatography (HPLC), and capillary electrophoresis (CE).